fuchs dystrophy Fuchs' Dystrophy Fuchs dystrophy is a slowly progressing disease that usually affects both eyes and is slightly more common in women than in men. Although doctors can often see early signs of Fuchs dystrophy in people in their 30s and 40s, the disease rarely affects vision until people reach their 50s and 60s. Fuchs dystrophy occurs when endothelial cells gradually deteriorate without any apparent reason. As more endothelial cells are lost over the years, the endothelium becomes less efficient at pumping water out of the stroma. This causes the cornea to swell and distort vision. Eventually, the epithelium also takes on water, resulting in pain and severe visual impairment. Epithelial swelling damages vision by changing the cornea's normal curvature, and causing a sight-impairing haze to appear in the tissue.  Epithelial swelling will also produce tiny blisters on the corneal surface. When these blisters burst, they are very painful. Fuchs Dystrophy Symptoms At first, a person with Fuchs dystrophy will awaken with blurred vision that will gradually clear during the day. This occurs because the cornea is normally thicker in the morning; it retains fluids during sleep that evaporate in the tear film while you are awake. As the disease worsens, this swelling will remain constant and reduce vision throughout the day. Fuchs Dystrophy Treatment When treating Fuchs Dystrophy disease, Opthamologists will try first to reduce the swelling with drops, ointments, or soft contact lenses. They also may instruct you to use a hair dryer, held at arm's length or directed across the face, to dry out the epithelial blisters. This can be done two or three times a day, depending on your Opthamologist's suggestions. When the disease interferes with daily activities, a person may need to consider having a corneal transplant to restore sight. The short-term success rate of corneal transplantation is quite good for people with Fuchs dystrophy.  Some studies suggest that the long-term survival of the new cornea can be a problem for the Fuchs Dystropy afflicted.